Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939610 | 0.90 | MAPT (0.58) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL7623001 | 0.87 | MAPT (0.60) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL6937560 | 0.86 | MEN1 (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6939392 | 0.83 | MEN1 (0.79) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6937520 | 0.83 | MEN1 (0.63) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL6941464 | 0.82 | MEN1 (0.68) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6939527 | 0.81 | KMT2A (0.67) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL6944035 | 0.81 | MAPT (0.59) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL6941539 | 0.81 | DDX3X (0.64) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6939929 | 0.81 | MAPT (0.62) | MEN1KMT2AMAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444691-B1 | ANTICHOLESTEROL AGENTS | SOLVAKOFARMA, A.S. (SK) | 2002-09-03 | — | — | US | disclosed |