SCHEMBL6937577

SCHEMBL6937577

COCCC(Oc1cc(-c2c(Cl)c(C(F)(F)F)n(C)c2Cl)c(F)cc1Cl)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.30
PPARA Q07869 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937922 0.89 PTGDR2 (0.36) PPARGPPARA
SCHEMBL6940986 0.85
SCHEMBL6937575 0.83 PTGDR2 (0.39) PPARG
SCHEMBL6937730 0.83 POLB (0.30)
SCHEMBL6935580 0.82 PTGDR2 (0.33) PPARGPPARA
SCHEMBL6937109 0.81 PTGDR2 (0.35) PPARGPPARA
SCHEMBL6937106 0.79 PTGDR2 (0.35) PPARGPPARA
SCHEMBL6940077 0.79 PTGDR2 (0.36) PPARGPPARA
SCHEMBL6937717 0.79 PPOX (0.35)
SCHEMBL6937330 0.78 PTGDR2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1061072-B1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA SRL (IT) 2003-05-14 EP disclosed
US-6391827-B1 CONTROLLING WEEDS ISAGRO RICERCA S.R.L. (IT) 2002-05-21 US disclosed
EP-1061072-A1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA S.r.l. (IT) 2000-12-20 EP disclosed