Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938036 | 0.92 | CYP2C19 (0.38) | PTGDR2RORCCYP2C19TDP1TSHR | |
| SCHEMBL6935030 | 0.92 | PTGDR2 (0.34) | PTGDR2RORCCYP2C19 | |
| SCHEMBL7693094 | 0.91 | LMNA (0.33) | PTGDR2RORCCYP2C19TDP1TSHR | |
| SCHEMBL6934937 | 0.91 | LMNA (0.33) | PTGDR2RORCCYP2C19TDP1TSHR | |
| SCHEMBL6939948 | 0.89 | CYP2C19 (0.38) | PTGDR2RORCCYP2C19TDP1TSHR | |
| SCHEMBL6937105 | 0.89 | KDM4E (0.36) | TSHRKDM4EALDH1A1HPGDHTT | |
| SCHEMBL6935585 | 0.88 | PPOX (0.46) | TDP1TSHRPKMKDM4EALDH1A1 | |
| SCHEMBL6934941 | 0.87 | CYP2C19 (0.38) | PTGDR2RORCCYP2C19TDP1TSHR | |
| SCHEMBL8094040 | 0.87 | CYP2C19 (0.40) | PTGDR2RORCCYP2C19TDP1TSHR | |
| SCHEMBL7702777 | 0.87 | LMNA (0.34) | TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061072-B1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA SRL (IT) | 2003-05-14 | — | — | EP | claimed |
| EP-1061072-B1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA SRL (IT) | 2003-05-14 | — | — | EP | disclosed |
| US-6391827-B1 | CONTROLLING WEEDS | ISAGRO RICERCA S.R.L. (IT) | 2002-05-21 | — | — | US | disclosed |
| EP-1061072-A1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA S.r.l. (IT) | 2000-12-20 | — | — | EP | disclosed |