Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937759 | 0.93 | CTNNB1 (0.67) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8674780 | 0.91 | CTNNB1 (0.53) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL27639122 | 0.86 | CTNNB1 (0.59) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL3953861 | 0.86 | CTNNB1 (0.62) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL3516701 | 0.86 | CTNNB1 (0.62) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8408147 | 0.85 | CTNNB1 (0.57) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL929771 | 0.84 | CTNNB1 (0.61) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8974791 | 0.83 | AKR1C3 (0.49) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL4425492 | 0.83 | CTNNB1 (0.59) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL6948356 | 0.82 | SLC6A3 (0.72) | SMN1; SMN2MEN1KMT2ASLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |