Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | BAX | Q07812 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937759 | 0.91 | CTNNB1 (0.67) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8408145 | 0.86 | CTNNB1 (0.61) | CTNNB1SMN1; SMN2LTA4HNR1H2BAX | |
| SCHEMBL6937765 | 0.85 | CTNNB1 (0.59) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL7184670 | 0.85 | KMT2A (0.54) | CTNNB1SMN1; SMN2LTA4HNR1H2BAX | |
| SCHEMBL3953861 | 0.84 | CTNNB1 (0.62) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL2355280 | 0.84 | CTNNB1 (0.58) | CTNNB1SMN1; SMN2LTA4HNR1H2BAX | |
| SCHEMBL3516701 | 0.84 | CTNNB1 (0.62) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL929771 | 0.83 | CTNNB1 (0.61) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8648432 | 0.82 | CTNNB1 (0.55) | CTNNB1SMN1; SMN2LTA4HNR1H2BAX | |
| SCHEMBL4425492 | 0.81 | CTNNB1 (0.59) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928912-A | EFFICIENT BIOSYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-27 | — | — | US | disclosed |