Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935322 | 0.79 | CYP19A1 (0.39) | SLC10A2CA1CA2CA9MAPT | |
| SCHEMBL6339069 | 0.69 | RECQL (0.36) | TDP1SLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL6932378 | 0.68 | CNR2 (0.37) | TDP1 | |
| SCHEMBL8181427 | 0.62 | HTT (0.48) | — | |
| SCHEMBL19117718 | 0.62 | SLC6A2 (0.40) | SLC10A2CA1CA2SLC6A2SLC6A4 | |
| SCHEMBL21266523 | 0.62 | SLC6A2 (0.40) | SLC10A2CA1CA2SLC6A2SLC6A4 | |
| SCHEMBL6557938 | 0.61 | BCHE (0.46) | — | |
| SCHEMBL21048271 | 0.60 | SLC10A2 (0.51) | SLC10A2 | |
| SCHEMBL6338888 | 0.60 | SLC6A2 (0.35) | TDP1SLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL11635613 | 0.59 | SLC6A2 (0.38) | SLC10A2SLC6A2SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915087-B1 | Sulfonamide substituted fused five-membered ring compounds, their use as medicaments as well as pharmaceutical compositions containing them | AVENTIS PHARMA GMBH (DE) | 2003-04-02 | — | — | EP | disclosed |
| US-6015822-A | ANTIULCER, ANTIDIARRHEA, AND ANTIARRHYTHMIA AGENTS; CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) | 2000-01-18 | — | — | US | disclosed |
| EP-0915087-A2 | Sulfonamide substituted fused five-membered ring compounds, their use as medicaments as well as pharmaceutical compositions containing them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-05-12 | — | — | EP | disclosed |