Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3851561 | 0.99 | MAPT (0.50) | ALDH1A1MAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL6535470 | 0.87 | PTPN1 (0.43) | ALDH1A1MAPTSMN1; SMN2RAB9AGAA | |
| Bromide SCHEMBL5004650 | 0.85 | PTPN1 (0.42) | ALDH1A1MAPTSMN1; SMN2RAB9AGAA | |
| Bromide SCHEMBL3845607 | 0.85 | PTPN1 (0.42) | ALDH1A1MAPTSMN1; SMN2RAB9AGAA | |
| SCHEMBL1820216 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2RAB9AHTT | |
| Bromide SCHEMBL3849504 | 0.84 | PTPN1 (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9AHTT | |
| Hydrochloric Acid SCHEMBL33828 | 0.84 | RAB9A (0.46) | ALDH1A1MAPTSMN1; SMN2RAB9AHTT | |
| Bromide SCHEMBL2954276 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL6939128 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9AHTT | |
| Bromide SCHEMBL3845606 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTRAB9AHTTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |