SCHEMBL6938281

SCHEMBL6938281

O=C(c1ccccc1Cl)C1CNCCO1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
SSTR4 P31391 6/20 0.44
RXFP1 Q9HBX9 1/20 0.43
SLC6A2 P23975 6/20 0.43
SLC6A4 P31645 4/20 0.43
SLC6A3 Q01959 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25214712 0.84 SSTR4 (0.43) SSTR4SLC6A2SLC6A4
SCHEMBL7753826 0.84 SSTR4 (0.43) SSTR4SLC6A2SLC6A4
SCHEMBL1042676 0.83 SSTR4 (0.45) SSTR4SLC6A2SLC6A4SLC6A3
SCHEMBL8543691 0.82 SSTR4 (0.42) SSTR4SLC6A2SLC6A4
SCHEMBL11446441 0.82 SSTR4 (0.42) SSTR4SLC6A2SLC6A4
SCHEMBL3996737 0.80 CHRNB2 (0.46) GAASSTR4SLC6A2SLC6A4
SCHEMBL50850 0.79 SLC6A2 (0.49) GAASSTR4SLC6A2SLC6A4SLC6A3
SCHEMBL8292968 0.78 SSTR4 (0.45) SSTR4SLC6A2SLC6A4
SCHEMBL3742282 0.78 SSTR4 (0.45) SSTR4SLC6A2SLC6A4
SCHEMBL4002672 0.78 SSTR4 (0.41) SSTR4SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1352731-A2 Method of orienting polymer molecules MISSISSIPPI POLYMER TECHNOLOGIES, INC. (US) 2003-10-15 EP disclosed
EP-0629217-B1 RIGID-ROD POLYMERS MISSISSIPPI POLYMER TECHNOLOGI (US) 2003-05-07 EP disclosed
US-6087467-A POLY-P-PHENYLENE AND SOLUBLE ORGANIC GROUPS MAXDEM INCORPORATED (US) 2000-07-11 US disclosed
US-5976437-A POLYPHENYL RESINS WITH PENDANT SOLUBILIZING GROUPS; MELT, WET, AND DRY-JET WET SPINNING; ORIENTING BY DRAWING OR STRETCHING; COATING SOLID ARTICLES MAXDEM INCORPORATED (US) 1999-11-02 US disclosed
US-5789521-A POLYPHENYL RESINS MAXDEM INCORPORATED (US) 1998-08-04 US disclosed
US-5760131-A IMPROVING THE FIRE RESISTANCE BY BLENDING WITH A POLYPHENYL RESINS MAXDEM INCORPORATED (US) 1998-06-02 US disclosed
US-5756581-A Rigid-rod polymers MAXDEM INCORPORATED (US) 1998-05-26 US disclosed
US-5731400-A FABRICATING FREE STANDING FILM OF SOLUBLE RIGID ROD POLYETHER SUBSTITUTED WITH SOLUBILIZING SIDE GROUP BY MELTING POLYMER AND EXTRUDING THROUGH SLIT MAXDEM INCORPORATED (US) 1998-03-24 US disclosed
US-5721335-A COMPRESSION MOLDING A POLYPHENYL RESIN HOMO- OR COPOLYMER; MELT PROCESSABILITY MAXDEM INCORPORATED (US) 1998-02-24 US disclosed
US-5654392-A POLYPHENYL RESINS HAVING SOLUBILIZING SIDE GROUPS MAXDEM INCORPORATED (US) 1997-08-05 US disclosed
US-5646232-A MANUFACTURING POLYPHENYL RESINS MAXDEM INCORPORATED (US) 1997-07-08 US disclosed
US-5646231-A POLYPHENYL RESINS MAXDEM, INCORPORATED (US) 1997-07-08 US disclosed
EP-0629217-A4 RIGID-ROD POLYMERS. MAXDEM INC (US) 1995-03-29 EP disclosed
EP-0629217-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1994-12-21 EP disclosed
WO-1993018077-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1993-09-16 WO disclosed
WO-1993018076-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1993-09-16 WO disclosed