Sulfuric Acid

Sulfuric Acid

SCHEMBL693831

O=S(=O)(O)O.[N-]=[N+]=N

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL19665193 0.96 CA5A (0.46)
Sulfuric Acid SCHEMBL9546784 0.96 CA5A (0.46)
SCHEMBL5632655 0.85
SCHEMBL11209834 0.85
Sulfuric Acid SCHEMBL2840688 0.82
SCHEMBL8763811 0.82 CA5A (0.40)
Sulfuric Acid SCHEMBL16448273 0.79 MEN1 (0.56)
Sulfuric Acid SCHEMBL28642679 0.78 CA5A (0.55)
Sulfuric Acid SCHEMBL16448274 0.78 CA5A (0.55)
Sulfuric Acid SCHEMBL3650810 0.78 CA5A (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070191393-A1 Macrocyclic anilinopyrimidines with substituted sulphoximine as selective inhibitors of cell cycle kinases BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-08-16 US claimed
JP-5331132-A None JP disclosed
US-20160303243-A1 ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE GLYCAN BIOSCIENCES LLC (US) 2016-10-20 US disclosed
US-9346845-B2 Anionic conjugates of glycosylated bacterial metabolite GLYCAN BIOSCIENCES LLC (US) 2016-05-24 US disclosed
US-20140323422-A1 Anionic Conjugates of Glycosylated Bacterial Metabolite Glycosynnovations Pty Ltd (AU) 2014-10-30 US disclosed
US-8791245-B2 Anionic conjugates of glycosylated bacterial metabolite Glycan Bioscience LLC (US) 2014-07-29 US disclosed
EP-2421877-A1 ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE Glycan Biosciences Pty Ltd (AU) 2012-02-29 EP disclosed
US-20110190233-A1 ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE GLYCAN BIOSCIENCES PTY LTD (AU) 2011-08-04 US disclosed
US-7825128-B2 Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs BAYER SCHERING PHARMA AG (DE) 2010-11-02 US disclosed
WO-2010037179-A1 ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE GLYCAN BIOSCIENCES PTY LTD (AU) 2010-04-08 WO disclosed
US-20070232632-A1 Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs BAYER INTELLECTUAL PROPERTY GMBH (DE) 2007-10-04 US disclosed
US-20070191393-A1 Macrocyclic anilinopyrimidines with substituted sulphoximine as selective inhibitors of cell cycle kinases BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-08-16 US disclosed
EP-0471592-B1 Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids DOW CHEMICAL CO (US) 1995-08-09 EP disclosed
JP-H05331132-A NEW SULFATE MCNEILAB INC 1993-12-14 JP disclosed
US-5236678-A Process for absorption of sulfur compounds from fluids using piperidines THE DOW CHEMICAL COMPANY (US) 1993-08-17 US disclosed
US-5167941-A Sulfur dioxide; cationic polyelectrolyte stabilizers THE DOW CHEMICAL COMPANY (US) 1992-12-01 US disclosed
EP-0471592-A2 Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids THE DOW CHEMICAL COMPANY (US) 1992-02-19 EP disclosed
US-4922019-A Derivatives of 2,2-bis-(3-aminophenyl)hexafluoropropane and process for the preparation of 2,2-bis-(3,4-diaminophenyl)hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-01 US disclosed
US-4486344-A CARBONYLDIIMIDAZOLE AS LINKING AGENT, IMMUNOASSY MILES LABORATORIES, INC. (US) 1984-12-04 US disclosed
EP-0123114-A1 Urea-linked immunogens, antibodies, and preparative method MILES LABORATORIES, INC. (US) 1984-10-31 EP disclosed