Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937477 | 0.99 | TXNRD1 (0.39) | SLC9A1TXNRD1GSR | |
| SCHEMBL6937306 | 0.97 | SLC9A1 (0.39) | SLC9A1 | |
| SCHEMBL6937498 | 0.92 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL7073664 | 0.90 | SLC9A1 (0.35) | SLC9A1TXNRD1GSR | |
| SCHEMBL6935243 | 0.89 | SLC9A1 (0.49) | SLC9A1 | |
| SCHEMBL6935428 | 0.89 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL7073129 | 0.88 | SLC9A1 (0.48) | SLC9A1 | |
| SCHEMBL6935494 | 0.86 | SLC9A1 (0.50) | SLC9A1 | |
| SCHEMBL6932512 | 0.84 | SLC9A1 (0.49) | SLC9A1 | |
| SCHEMBL8539439 | 0.83 | TXNRD1 (0.44) | TXNRD1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758644-B1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0758644-A1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GmbH (DE) | 1997-02-19 | — | — | EP | disclosed |