Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13933057 | 0.89 | MAPT (0.52) | MAPTPPARGPPARALTB4RCNR2 | |
| SCHEMBL16788118 | 0.81 | GAA (0.51) | TSHRMAPTALDH1A1CYP1A2KDM4E | |
| SCHEMBL13214929 | 0.80 | MAPT (0.56) | TSHRMAPTHDAC8CNR2ALDH1A1 | |
| SCHEMBL25376422 | 0.79 | ALDH1A1 (0.44) | TSHRMAPTPPARGPPARAALDH1A1 | |
| SCHEMBL693224 | 0.79 | MAPT (0.59) | TSHRMAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11689573 | 0.78 | TSHR (0.62) | TSHRPPARGPPARAALDH1A1CYP1A2 | |
| SCHEMBL17262864 | 0.78 | HDAC1 (0.50) | MAPTHDAC8ALDH1A1GAAHSD17B10 | |
| SCHEMBL13933074 | 0.78 | HDAC1 (0.50) | MAPTHDAC8ALDH1A1GAAHSD17B10 | |
| SCHEMBL831000 | 0.78 | HDAC1 (0.50) | MAPTHDAC8ALDH1A1GAAHSD17B10 | |
| SCHEMBL14570540 | 0.78 | PPARG (0.56) | PPARGPPARACNR2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2422817-A1 | Flavin-nucleic acid ligand conjugates | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2012-02-29 | — | — | EP | disclosed |