Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654525 | 0.83 | PTGS2 (0.54) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL18689537 | 0.80 | PTGS2 (0.58) | MAPTALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL831490 | 0.80 | PTGS2 (0.58) | MAPTALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL28199847 | 0.80 | PTGS2 (0.58) | MAPTALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL89210 | 0.80 | MAPT (0.55) | MAPTALDH1A1POLBNPC1KMT2A | |
| SCHEMBL693846 | 0.79 | TSHR (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27630962 | 0.78 | CYP19A1 (0.55) | MAPTALDH1A1NPC1KMT2ACYP19A1 | |
| SCHEMBL16943506 | 0.78 | ALDH1A1 (0.53) | MAPTALDH1A1POLBNPC1KMT2A | |
| SCHEMBL14363209 | 0.78 | MAPT (0.53) | MAPTALDH1A1POLBKMT2ACYP19A1 | |
| SCHEMBL10051650 | 0.78 | ALDH1A1 (0.56) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2422817-A1 | Flavin-nucleic acid ligand conjugates | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2012-02-29 | — | — | EP | disclosed |