SCHEMBL6938609

SCHEMBL6938609

COc1ccc(N)cc1S(=O)(=O)CCOS(=O)(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.39
MAPT P10636 5/20 0.39
GAA P10253 3/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 3/20 0.39
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
USP2 O75604 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CA5A P35218 1/20 0.36
CYP19A1 P11511 1/20 0.36
LMNA P02545 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10948058 0.88 HSD17B10 (0.38) HSD17B10MAPTGAAALDH1A1KDM4E
SCHEMBL11670686 0.86 HSD17B10 (0.51) HSD17B10MAPTGAAALDH1A1KDM4E
SCHEMBL9138757 0.86 HSD17B10 (0.39) HSD17B10MAPTGAAALDH1A1KDM4E
SCHEMBL9414558 0.85 MAPT (0.41) HSD17B10MAPTGAAALDH1A1KDM4E
SCHEMBL22375856 0.84 L3MBTL1 (0.51) MAPTGAAALDH1A1MAPK1SMN1; SMN2
SCHEMBL13892251 0.84 POLB (0.49) HSD17B10GAATSHRMAPK1HTT
SCHEMBL8165270 0.84 CA2 (0.44) MAPTGAAALDH1A1KDM4EPKM
SCHEMBL8951824 0.83 HSD17B10 (0.37) HSD17B10MAPTGAAALDH1A1KDM4E
SCHEMBL8818789 0.83 MAPT (0.38) MAPTGAAKDM4EPKMTSHR
SCHEMBL6937844 0.82 L3MBTL1 (0.40) HSD17B10MAPTGAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997025472-A1 METHOD OF PRODUCING COLOURED NATURAL OR SYNTHETIC SUBSTRATES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1997-07-17 WO claimed
JP-8295818-A None JP disclosed
EP-1090962-B1 Dye mixtures of fiber-reactive azo dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-05-14 EP disclosed
EP-0979848-B1 Orange dye mixtures of fiber-reactive azo dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-04-17 EP disclosed
EP-1090962-A2 Dye mixtures of fiber-reactive azo dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-04-11 EP disclosed
US-6159251-A Dye mixtures of fiber-reactive azo dyes and use thereof for dyeing material containing hydroxy-and/or carboxamido groups DYSTAR TEXTILFARBON GMBH & CO. DEUTSCHLAND KG (DE) 2000-12-12 US disclosed
EP-1013818-A2 Dyeing process Avecia Limited (GB) 2000-06-28 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
EP-0979848-A1 Orange dye mixtures of fiber-reactive azo dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-02-16 EP disclosed
US-5980590-A HIGH COLOR YIELD; FOR DYEING OR PRINTING OF CELLULOSIC FIBERS, WOOL, AND POLYAMIDE FIBERS DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-11-09 US disclosed
US-4713082-A Process for dyeing or printing textile fibre materials with reactive dye containing vinyl sulfonyl-type group and chloro-triazinyl amino group CIBA-GEIGY CORPORATION (US) 1987-12-15 US disclosed
US-4709018-A COLORFAST CIBA-GEIGY CORPORATION (US) 1987-11-24 US disclosed
EP-0242850-A1 Water soluble monoazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-28 EP disclosed
EP-0231836-A2 Water soluble disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-12 EP disclosed
US-4576755-A Water-soluble fibre-reactive phthalocyanine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-18 US disclosed
US-4394310-A DIAZOTIZATION, CYCLIZATION HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-19 US disclosed
US-4283196-A FIXING BY ACTION OF AN ALKALINE AGENT AMERICAN HOECHST CORPORATION (US) 1981-08-11 US disclosed
US-4271072-A FIBER-REACTIVE, FOR DYEING NATURAL AND SYNTHETIC POLYAMIDES AND CELULOSES AMERICAN HOECHST CORPORATION (US) 1981-06-02 US disclosed
EP-0022265-A2 Reactive bisazo dyes, a process for their production and their use for dyeing cellulose fibers and cellulosic textiles SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-14 EP disclosed
US-4035350-A Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed