Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758238 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11039228 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11292065 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11293624 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11412458 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL578183 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11408403 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12993821 | 0.98 | ALDH1A1 (0.61) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9468217 | 0.93 | ALDH1A1 (0.52) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9468140 | 0.93 | ALDH1A1 (0.52) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576623-B1 | Compound or polymer containing siloxane and oxyalkylene groups; nonoily; spreads easily and smoothly; moist, fresh, dry feel; storage and heat stability | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1072627-B1 | Silicone compound and cosmetic materials containing the same | SHINETSU CHEMICAL CO (JP) | 2003-03-19 | — | — | EP | disclosed |
| EP-1072627-A2 | Silicone compound and cosmetic materials containing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |