Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935907 | 0.88 | ADORA2A (0.43) | DYRK1ACLK4BACE1KCNH2ADORA2A | |
| SCHEMBL29888758 | 0.88 | ADORA2A (0.43) | DYRK1ACLK4BACE1KCNH2ADORA2A | |
| SCHEMBL6935532 | 0.83 | DYRK1A (0.41) | DYRK1ACLK4BACE1KCNH2ADORA2A | |
| SCHEMBL29897699 | 0.83 | DYRK1A (0.41) | DYRK1ACLK4BACE1KCNH2ADORA2A | |
| SCHEMBL8666635 | 0.81 | DYRK1A (0.44) | DYRK1ACLK4BACE1KCNH2ADORA2A | |
| SCHEMBL30040209 | 0.80 | DYRK1A (0.46) | DYRK1ACLK4BACE1KCNH2ADORA2A | |
| SCHEMBL6940381 | 0.80 | DYRK1A (0.46) | DYRK1ACLK4BACE1KCNH2ADORA2A | |
| SCHEMBL6937716 | 0.80 | BACE1 (0.45) | DYRK1ACLK4BACE1NPY5RNCOA1 | |
| SCHEMBL29450716 | 0.80 | BACE1 (0.45) | DYRK1ACLK4BACE1NPY5RNCOA1 | |
| SCHEMBL6941655 | 0.80 | DYRK1A (0.43) | DYRK1ACLK4BACE1KCNH2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6524770-B1 | For polyimide precursor curable under patternwise low radiation; heat and chemical resistance; polyamide having unsaturated ester pendant groups cures | HITACHI CHEMICAL CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |