Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938329 | 0.91 | HTT (0.46) | HPGDHTTMEN1LMNAMAPT | |
| SCHEMBL6936437 | 0.88 | HPGD (0.48) | HPGDHTTMEN1LMNAMAPT | |
| SCHEMBL7044950 | 0.81 | HPGD (0.49) | HPGDHTTMEN1LMNAMAPT | |
| SCHEMBL9303754 | 0.81 | ALDH1A1 (0.48) | HPGDHTTMEN1LMNAMAPT | |
| SCHEMBL31657717 | 0.81 | ALDH1A1 (0.48) | HPGDHTTMEN1LMNAMAPT | |
| SCHEMBL2925754 | 0.79 | SELL (0.52) | HPGDHTTMEN1LMNAMAPT | |
| SCHEMBL8957203 | 0.78 | ALDH1A1 (0.44) | HPGDHTTMEN1LMNAMAPT | |
| SCHEMBL8957163 | 0.78 | SRD5A1 (0.43) | HPGDHTTMEN1LMNAMAPT | |
| SCHEMBL3961509 | 0.77 | CA12 (0.47) | HPGDHTTMEN1LMNAMAPT | |
| SCHEMBL63797 | 0.77 | ALDH1A1 (0.55) | HPGDHTTMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |