SCHEMBL6939701

SCHEMBL6939701

C#CCOc1cc(-c2c(Cl)c(C(F)(F)F)n(OC)c2Cl)c(F)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.34
EGFR P00533 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937162 0.87 PGK1 (0.35) PGK1LMNA
SCHEMBL6940394 0.85 PGK1 (0.36) PGK1LMNA
SCHEMBL6939644 0.83 PGK1 (0.35) PGK1LMNA
SCHEMBL8094040 0.82 CYP2C19 (0.40) LMNA
SCHEMBL6937859 0.81 PGK1 (0.34) PGK1EGFRLMNA
SCHEMBL6932316 0.79 PGK1 (0.34) PGK1LMNA
SCHEMBL6936945 0.77 PGK1 (0.34) PGK1LMNA
SCHEMBL6940401 0.77 NR1I2 (0.31)
SCHEMBL6934923 0.77 PGK1 (0.37) PGK1EGFRLMNA
SCHEMBL6906104 0.76 PGK1 (0.37) PGK1EGFRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1061072-B1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA SRL (IT) 2003-05-14 EP disclosed
US-6391827-B1 CONTROLLING WEEDS ISAGRO RICERCA S.R.L. (IT) 2002-05-21 US disclosed
EP-1061072-A1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA S.r.l. (IT) 2000-12-20 EP disclosed