SCHEMBL6936945

SCHEMBL6936945

C#CCOc1cc(-c2c(Br)c(C(F)(F)F)n(C)c2Br)c(F)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.34
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6932316 0.92 PGK1 (0.34) PGK1LMNA
SCHEMBL6937162 0.83 PGK1 (0.35) PGK1LMNA
SCHEMBL6940513 0.82 CYP2C19 (0.38)
SCHEMBL6937089 0.81 PGK1 (0.35) PGK1PDCD1CD274LMNA
SCHEMBL6935624 0.79 PPOX (0.45) LMNA
SCHEMBL6939644 0.78 PGK1 (0.35) PGK1LMNA
SCHEMBL5773913 0.77 PGK1 (0.34) PGK1LMNA
SCHEMBL6940394 0.77 PGK1 (0.36) PGK1LMNA
SCHEMBL6937859 0.77 PGK1 (0.34) PGK1LMNA
SCHEMBL6939701 0.77 PGK1 (0.34) PGK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1061072-B1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA SRL (IT) 2003-05-14 EP claimed
EP-1061072-B1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA SRL (IT) 2003-05-14 EP disclosed