Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869696 | 0.86 | SLC6A4 (0.62) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL6936270 | 0.84 | SLC6A4 (0.54) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL6941934 | 0.84 | SLC6A4 (0.56) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL6865381 | 0.82 | SLC6A2 (0.60) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL8686122 | 0.81 | SLC6A2 (0.59) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL150032 | 0.80 | SLC6A4 (0.73) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL6943206 | 0.78 | SLC6A4 (0.62) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL13950732 | 0.77 | SLC6A4 (0.65) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL4311051 | 0.77 | SLC6A4 (0.65) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL15127712 | 0.77 | SLC6A4 (0.65) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368299-A2 | SUBSTITUTED C-CYCLOHEXYLMETHYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2003-12-10 | — | — | EP | claimed |
| WO-2002030870-A2 | SUBSTITUTED C-CYCLOHEXYLMETHYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2002-04-18 | — | — | WO | claimed |