Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28739210 | 0.87 | SLC6A4 (0.64) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 | |
| SCHEMBL28739224 | 0.85 | SLC6A4 (0.62) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 | |
| SCHEMBL28739230 | 0.85 | SLC6A4 (0.62) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 | |
| SCHEMBL5880550 | 0.85 | SLC6A4 (0.62) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 | |
| SCHEMBL6943206 | 0.85 | SLC6A4 (0.62) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 | |
| SCHEMBL28739239 | 0.85 | SLC6A4 (0.62) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 | |
| SCHEMBL6342861 | 0.85 | SLC6A4 (0.65) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 | |
| Desmetramadol SCHEMBL57246 | 0.85 | OPRM1 (1.00) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 | |
| SCHEMBL7921501 | 0.85 | SLC6A4 (0.77) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 | |
| O-Desmethyl Tramadol SCHEMBL4396389 | 0.85 | OPRM1 (1.00) | SLC6A4SLC6A2OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176790-A1 | Pharmaceutical salts | GRUNENTHAL GMBH (DE) | 2005-08-11 | — | — | US | claimed |
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | claimed |
| US-5801201-A | 1-phenyl-2-dimenthylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients | GRUENENTHAL GMBH (DE) | 1998-09-01 | — | — | US | claimed |
| JP-9221460-A | — | — | None | — | — | JP | disclosed |
| CN-114426494-B | Substituted methylamine derivatives acting on TAAR agonist | 江苏海洋大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-114426494-A | Substituted methylamine derivative acting on TAAR agonist | 江苏海洋大学 | 2022-05-03 | — | — | CN | disclosed |
| US-10160719-B2 | Pharmaceutical salts | GRUNENTHAL GMBH (DE) | 2018-12-25 | — | — | US | disclosed |
| US-20170137370-A1 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20120059066-A1 | PHARMACEUTICAL SALTS | GRUNENTHAL GMBH (DE) | 2012-03-08 | — | — | US | disclosed |
| US-20090258948-A1 | PHARMACEUTICAL SALTS | GRUNENTHAL GMBH (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20050176790-A1 | Pharmaceutical salts | GRUNENTHAL GMBH (DE) | 2005-08-11 | — | — | US | disclosed |
| CN-1071309-C | 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients | GROUNENTHAL GMBH (DE) | 2001-09-19 | — | — | CN | disclosed |
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| US-5801201-A | 1-phenyl-2-dimenthylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients | GRUENENTHAL GMBH (DE) | 1998-09-01 | — | — | US | disclosed |
| US-5801201-A | 1-phenyl-2-dimenthylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients | GRUENENTHAL GMBH (DE) | 1998-09-01 | — | — | US | disclosed |
| CN-1157815-A | 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients | GRUENENTHAL GMBH (DE) | 1997-08-27 | — | — | CN | disclosed |
| CN-1157815-A | 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients | GRUENENTHAL GMBH (DE) | 1997-08-27 | — | — | CN | disclosed |
| JP-H09221460-A | 1-PHENYL-2-DIMETHYLAMINOMETHYLCYCLOHEXAN-1-OL COMPOUND AS PHARMACEUTICALLY EFFECTIVE MATERIAL | GRUENENTHAL GMBH | 1997-08-26 | — | — | JP | disclosed |
| EP-0780369-A1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-06-25 | — | — | EP | disclosed |
| EP-0780369-A1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176790-A1 | Pharmaceutical salts | SLC5A1, SLC5A2, SLC35A1 | SLC6A4 106/4885SLC6A2 217/4885OPRM1 2171/4885 |
| US-20120059066-A1 | PHARMACEUTICAL SALTS | SLC5A1, SLC5A2, SLC35A1 | SLC6A4 83/4885SLC6A2 164/4885OPRM1 2283/4885 |
| US-10160719-B2 | Pharmaceutical salts | SLC5A1, SLC5A2, SLC35A1 | SLC6A4 83/4885SLC6A2 164/4885OPRM1 2283/4885 |
| US-20170137370-A1 | PHARMACEUTICAL SALTS | SLC5A1, SLC5A2, SLC35A1 | SLC6A4 83/4885SLC6A2 164/4885OPRM1 2283/4885 |
| US-20090258948-A1 | PHARMACEUTICAL SALTS | SLC5A1, SLC5A2, SLC35A1 | SLC6A4 83/4885SLC6A2 164/4885OPRM1 2283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.