Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2954113 | 0.98 | KMT2A (0.55) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL6939311 | 0.88 | KMT2A (0.57) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| Bromide SCHEMBL2953526 | 0.87 | KMT2A (0.59) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL6936085 | 0.85 | ALDH1A1 (0.57) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| Bromide SCHEMBL2951033 | 0.83 | ALDH1A1 (0.60) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| Bromide SCHEMBL8390275 | 0.83 | ALDH1A1 (0.60) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| Bromide SCHEMBL8390272 | 0.82 | ALDH1A1 (0.58) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| Bromide SCHEMBL3965832 | 0.81 | HSD11B1 (0.44) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL6937917 | 0.81 | TDP1 (0.55) | KMT2AKDM4EMEN1HPGDMAPT | |
| Bromide SCHEMBL3846583 | 0.80 | KDM4E (0.56) | KMT2AKDM4EALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38330-E1 | Preventing and reversing advanced glycosylation endproducts | ALTEON INC. | 2003-11-25 | — | — | US | claimed |
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |