Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805571 | 1.00 | PPARG (0.78) | PPARGPPARA | |
| SCHEMBL8804769 | 0.95 | PPARG (0.85) | PPARGPPARA | |
| SCHEMBL8804303 | 0.95 | PPARG (0.85) | PPARGPPARA | |
| SCHEMBL5994062 | 0.89 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL8804772 | 0.88 | PPARG (0.77) | PPARGPPARA | |
| SCHEMBL8804308 | 0.88 | PPARG (0.77) | PPARGPPARA | |
| SCHEMBL5379904 | 0.86 | PPARG (0.78) | PPARGPPARA | |
| SCHEMBL6713386 | 0.86 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL5484591 | 0.85 | PPARG (0.87) | PPARGPPARA | |
| SCHEMBL8807305 | 0.85 | PPARG (0.62) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| CN-1219927-A | Phenylalkylcarboxylic acid derivatives | SANKYO CO (JP) | 1999-06-16 | — | — | CN | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5438074-A | 3-aryl-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents | PFIZER INC. (US) | 1995-08-01 | — | — | US | disclosed |
| US-5306726-A | 3-aryl-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents | PFIZER INC. (US) | 1994-04-26 | — | — | US | disclosed |
| US-5232945-A | 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives | PFIZER INC. (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0533781-A1 | 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVES AND ANALOGS AS HYPOGLYCEMIC AGENTS. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019702-A1 | 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVES AND ANALOGS AS HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1991-12-26 | — | — | WO | disclosed |