Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 4/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 3/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943975 | 0.91 | ADAM17 (0.56) | ADAM17TGFBR1P2RX3KMT2AMMP2 | |
| SCHEMBL6946243 | 0.90 | ADAM17 (0.53) | ADAM17TGFBR1P2RX3MMP2MMP9 | |
| SCHEMBL6943561 | 0.89 | ADAM17 (0.67) | ADAM17TGFBR1P2RX3KMT2AMMP2 | |
| SCHEMBL6939910 | 0.89 | ADAM17 (0.57) | ADAM17TGFBR1P2RX3KMT2AMMP2 | |
| SCHEMBL6947109 | 0.89 | ADAM17 (0.57) | ADAM17TGFBR1P2RX3KMT2AMMP2 | |
| SCHEMBL6939914 | 0.89 | ADAM17 (0.57) | ADAM17TGFBR1P2RX3KMT2AMMP2 | |
| SCHEMBL6945333 | 0.88 | ADAM17 (0.55) | ADAM17TGFBR1P2RX3KMT2AMMP2 | |
| SCHEMBL7103578 | 0.88 | ADAM17 (0.50) | ADAM17CNR2SMN1; SMN2MAPK1TGFBR1 | |
| SCHEMBL6942461 | 0.88 | ADAM17 (0.56) | ADAM17TGFBR1P2RX3MMP2MMP9 | |
| SCHEMBL6945556 | 0.88 | ADAM17 (0.58) | ADAM17TGFBR1P2RX3MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |