Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105146 | 0.90 | ADAM17 (0.55) | ADAM17TGFBR1 | |
| SCHEMBL7100568 | 0.89 | ADAM17 (0.53) | ADAM17TGFBR1 | |
| SCHEMBL6939853 | 0.88 | ADAM17 (0.53) | ADAM17CNR2MAPK1SMN1; SMN2TGFBR1 | |
| SCHEMBL7104739 | 0.87 | ADAM17 (0.52) | ADAM17 | |
| SCHEMBL6943561 | 0.87 | ADAM17 (0.67) | ADAM17TGFBR1KMT2A | |
| SCHEMBL7100919 | 0.86 | ADAM17 (0.51) | ADAM17 | |
| SCHEMBL7104728 | 0.85 | ADAM17 (0.69) | ADAM17 | |
| Hydrochloric Acid SCHEMBL7104766 | 0.84 | ADAM17 (0.68) | ADAM17 | |
| SCHEMBL6945556 | 0.83 | ADAM17 (0.58) | ADAM17TGFBR1 | |
| SCHEMBL6947109 | 0.83 | ADAM17 (0.57) | ADAM17TGFBR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133471-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6265446-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASES | HOFFMANN-LA ROCHE INC.. | 2001-07-24 | — | — | US | disclosed |