Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 12/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22541020 | 0.71 | CYP2A6 (0.48) | ALOX15TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL6822784 | 0.70 | SRD5A1 (1.00) | SRD5A1 | |
| SCHEMBL20622247 | 0.68 | CYP2A6 (0.48) | SRD5A1ALOX15TSHRDDB1CRBN | |
| SCHEMBL22546361 | 0.65 | CYP2A6 (0.44) | SRD5A1TSHRDDB1CRBNMEN1 | |
| SCHEMBL4865019 | 0.64 | KMT2A (0.51) | TSHRMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL25026229 | 0.64 | ALDH1A1 (0.55) | SRD5A1ALOX15TSHRBRCA1DDB1 | |
| SCHEMBL10460338 | 0.63 | CYP1A2 (0.58) | MEN1ALDH1A1KMT2ACYP2A6NOTUM | |
| SCHEMBL20598840 | 0.62 | DDB1 (0.50) | ALOX15DDB1CRBNMEN1ALDH1A1 | |
| SCHEMBL16799216 | 0.62 | ALOX5 (0.46) | ALOX15TSHRALDH1A1 | |
| SCHEMBL2392480 | 0.61 | ALDH1A1 (0.39) | ALOX15TSHRMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880520-B1 | BENZO [C]QUINOLIZINE DERIVATIVES, THEIR PREPARATION AND USE AS 5-ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2003-04-16 | — | — | EP | claimed |