SCHEMBL69400

SCHEMBL69400

COC(=O)c1cc(C(=O)OC)n(-c2ccccc2)n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.60
HPGD P15428 3/20 0.50
KDM4E B2RXH2 3/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
RECQL P46063 1/20 0.48
ALDH1A1 P00352 7/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
POLB P06746 1/20 0.48
CYP1A2 P05177 1/20 0.48
TP53 P04637 1/20 0.48
GAA P10253 2/20 0.48
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GRN P28799 1/20 0.47
SORT1 Q99523 1/20 0.47
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10568581 0.86 KDM4E (0.51) SMN1; SMN2HPGDKDM4EMAPTKMT2A
SCHEMBL7056604 0.85 ALDH1A1 (0.54) SMN1; SMN2HPGDKDM4EMAPTKMT2A
SCHEMBL28644955 0.84 HPGD (0.50) SMN1; SMN2HPGDKDM4EMAPTKMT2A
SCHEMBL4850604 0.84 SMN1; SMN2 (0.60) SMN1; SMN2HPGDKDM4EMAPTKMT2A
SCHEMBL28825868 0.84 ALDH1A1 (0.62) SMN1; SMN2HPGDMAPTKMT2AALDH1A1
SCHEMBL16112346 0.83 SMN1; SMN2 (0.62) SMN1; SMN2HPGDKDM4EMAPTKMT2A
SCHEMBL28923697 0.83 SMN1; SMN2 (0.59) SMN1; SMN2HPGDKDM4EMAPTKMT2A
SCHEMBL20028706 0.83 SMN1; SMN2 (0.59) SMN1; SMN2HPGDKDM4EMAPTKMT2A
SCHEMBL16112407 0.83 SMN1; SMN2 (0.59) SMN1; SMN2HPGDKDM4EMAPTKMT2A
SCHEMBL11649636 0.83 HPGD (0.59) SMN1; SMN2HPGDKDM4EMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 SMN1; SMN2 4357/4885HPGD 3275/4885KDM4E 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.