Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696732 | 0.92 | CTSS (0.41) | CTSS | |
| SCHEMBL700242 | 0.84 | CTSS (0.58) | CTSSCTSL | |
| SCHEMBL693999 | 0.84 | CTSS (0.48) | CTSSCTSL | |
| SCHEMBL696428 | 0.84 | CTSS (0.48) | CTSSCTSL | |
| SCHEMBL15173447 | 0.83 | CTSL (0.44) | CTSSCTSL | |
| SCHEMBL696670 | 0.82 | CTSS (0.51) | CTSSCTSL | |
| SCHEMBL694782 | 0.81 | CTSS (0.52) | CTSSCTSL | |
| SCHEMBL695175 | 0.80 | CTSS (0.55) | CTSSCTSL | |
| SCHEMBL695616 | 0.80 | CTSS (0.59) | CTSSCTSL | |
| SCHEMBL696102 | 0.80 | CTSS (0.40) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2012-02-29 | — | — | EP | claimed |
| WO-2010121918-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-10-28 | — | — | WO | claimed |
| EP-2421826-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010121918-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-10-28 | — | — | WO | disclosed |