SCHEMBL6940107

SCHEMBL6940107

O=C1C[C@H](Nc2ccc(N[C@H]3CC(=O)NC3=O)cc2)C(=O)N1

nearest known ligand 0.75

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.75
TSHR P16473 1/20 0.75
DDB1 Q16531 17/20 0.57
CRBN Q96SW2 17/20 0.57
MAP3K14 Q99558 1/20 0.40
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9326554 0.90 DDB1 (0.70) GAATSHRDDB1CRBN
SCHEMBL22144430 0.84 GAA (0.57) GAATSHRDDB1CRBN
SCHEMBL22119641 0.78 TSHR (0.50) GAATSHRDDB1CRBN
SCHEMBL15864812 0.75 MAP3K14 (0.48) GAATSHRDDB1CRBNMAP3K14
SCHEMBL25217798 0.73 DDB1 (0.67) GAATSHRDDB1CRBN
SCHEMBL21965448 0.73 DDB1 (0.72) GAATSHRDDB1CRBN
SCHEMBL21965374 0.73 DDB1 (0.72) DDB1CRBN
SCHEMBL23551584 0.73 DDB1 (0.72) DDB1CRBN
SCHEMBL21965393 0.73 DDB1 (1.00) DDB1CRBN
SCHEMBL23551219 0.73 DDB1 (0.72) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1016659-B1 Bismaleimides comprising mesogenic groups and oligomeric liquid crystalline bismaleimides DAINIPPON INK & CHEMICALS (JP) 2003-09-24 EP disclosed
US-6169186-B1 LIQUID CRYSTALS AND LIQUID CRYSTALLINE POLYMERS DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-01-02 US disclosed
EP-1016659-A1 Bismaleimides comprising mesogenic groups and oligomeric liquid crystalline bismaleimides DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-07-05 EP disclosed