SCHEMBL6940233

SCHEMBL6940233

Cc1cccc(C(=O)c2cc(Cl)ccc2Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.56
MAPT P10636 3/20 0.56
LMNA P02545 3/20 0.56
HPGD P15428 2/20 0.56
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
HTT P42858 1/20 0.56
KMT2A Q03164 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
POLB P06746 1/20 0.55
CNR2 P34972 1/20 0.51
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
PKM P14618 1/20 0.51
KCNK3 O14649 3/20 0.49
KCNK9 Q9NPC2 2/20 0.49
TP53 P04637 2/20 0.49
ALDH1A1 P00352 2/20 0.49
FGFR1 P11362 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14419290 0.86 KMT2A (0.70) SMN1; SMN2MAPTLMNAHPGDKDM4E
SCHEMBL27860 0.86 MAPT (0.55) SMN1; SMN2MAPTLMNAHPGDKDM4E
SCHEMBL9207127 0.84 POLB (0.69) SMN1; SMN2MAPTLMNAHPGDKDM4E
SCHEMBL9207086 0.84 POLB (0.69) SMN1; SMN2MAPTLMNAHPGDKDM4E
SCHEMBL23409104 0.82 POLB (0.56) SMN1; SMN2MAPTLMNAHPGDKDM4E
SCHEMBL4342906 0.81 MAPT (0.53) SMN1; SMN2MAPTLMNAHPGDKDM4E
SCHEMBL11504405 0.81 KCNK3 (0.64) SMN1; SMN2MAPTLMNAHPGDKDM4E
SCHEMBL230930 0.81 ALDH1A1 (0.63) SMN1; SMN2MAPTLMNAHPGDMEN1
SCHEMBL29612638 0.81 ALDH1A1 (0.63) SMN1; SMN2MAPTLMNAHPGDMEN1
SCHEMBL15751198 0.81 GRIK1 (0.51) MAPTLMNAMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1619739-B1 Membrane-electrode structure for solid polymer fuel cell and solid polymer fuel cell HONDA MOTOR CO LTD (JP) 2010-09-22 EP disclosed
EP-1352731-A2 Method of orienting polymer molecules MISSISSIPPI POLYMER TECHNOLOGIES, INC. (US) 2003-10-15 EP disclosed
EP-0629217-B1 RIGID-ROD POLYMERS MISSISSIPPI POLYMER TECHNOLOGI (US) 2003-05-07 EP disclosed
US-6087467-A POLY-P-PHENYLENE AND SOLUBLE ORGANIC GROUPS MAXDEM INCORPORATED (US) 2000-07-11 US disclosed
US-5976437-A POLYPHENYL RESINS WITH PENDANT SOLUBILIZING GROUPS; MELT, WET, AND DRY-JET WET SPINNING; ORIENTING BY DRAWING OR STRETCHING; COATING SOLID ARTICLES MAXDEM INCORPORATED (US) 1999-11-02 US disclosed
US-5789521-A POLYPHENYL RESINS MAXDEM INCORPORATED (US) 1998-08-04 US disclosed
US-5760131-A IMPROVING THE FIRE RESISTANCE BY BLENDING WITH A POLYPHENYL RESINS MAXDEM INCORPORATED (US) 1998-06-02 US disclosed
US-5756581-A Rigid-rod polymers MAXDEM INCORPORATED (US) 1998-05-26 US disclosed
US-5731400-A FABRICATING FREE STANDING FILM OF SOLUBLE RIGID ROD POLYETHER SUBSTITUTED WITH SOLUBILIZING SIDE GROUP BY MELTING POLYMER AND EXTRUDING THROUGH SLIT MAXDEM INCORPORATED (US) 1998-03-24 US disclosed
US-5721335-A COMPRESSION MOLDING A POLYPHENYL RESIN HOMO- OR COPOLYMER; MELT PROCESSABILITY MAXDEM INCORPORATED (US) 1998-02-24 US disclosed
US-5654392-A POLYPHENYL RESINS HAVING SOLUBILIZING SIDE GROUPS MAXDEM INCORPORATED (US) 1997-08-05 US disclosed
US-5646232-A MANUFACTURING POLYPHENYL RESINS MAXDEM INCORPORATED (US) 1997-07-08 US disclosed
US-5646231-A POLYPHENYL RESINS MAXDEM, INCORPORATED (US) 1997-07-08 US disclosed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO disclosed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US disclosed