Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 7/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2903491 | 1.00 | CASP2 (0.59) | CASP2FAAHEPHX2NAAASLC6A5 | |
| Acetic Acid SCHEMBL2906531 | 1.00 | CASP2 (0.59) | CASP2FAAHEPHX2NAAASLC6A5 | |
| Acetic Acid SCHEMBL6138982 | 1.00 | CASP2 (0.59) | CASP2FAAHEPHX2NAAASLC6A5 | |
| Acetic Acid SCHEMBL6138704 | 1.00 | CASP2 (0.59) | CASP2FAAHEPHX2NAAASLC6A5 | |
| Acetic Acid SCHEMBL6939789 | 1.00 | CASP2 (0.59) | CASP2FAAHEPHX2NAAASLC6A5 | |
| Acetic Acid SCHEMBL6139358 | 1.00 | CASP2 (0.59) | CASP2FAAHEPHX2NAAASLC6A5 | |
| Acetic Acid SCHEMBL6935928 | 0.97 | FAAH (0.57) | CASP2FAAHEPHX2NAAASLC6A5 | |
| Acetic Acid SCHEMBL6139074 | 0.97 | FAAH (0.57) | CASP2FAAHEPHX2NAAASLC6A5 | |
| Acetic Acid SCHEMBL6940704 | 0.95 | FAAH (0.56) | CASP2FAAHEPHX2NAAASLC6A5 | |
| SCHEMBL24087524 | 0.95 | CASP2 (0.65) | CASP2FAAHEPHX2NAAASLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285579-A1 | Bactericidal guanidine derivatives, dermally applicable composition, washing composition, and antibacterial fibre aggregate | Ajinomoto Co., Inc. (JP) | 2003-02-26 | — | — | EP | disclosed |