Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.68 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365759 | 1.00 | PLAU (0.68) | PLAUIDO1SIGMAR1ANPEPFYN | |
| Hydrochloric Acid SCHEMBL29384401 | 0.97 | PLAU (0.65) | PLAUIDO1SIGMAR1ANPEPFYN | |
| Hydrochloric Acid SCHEMBL151479 | 0.97 | PLAU (0.65) | PLAUIDO1SIGMAR1ANPEPFYN | |
| Hydrochloric Acid SCHEMBL4543313 | 0.94 | PLAU (0.62) | PLAUIDO1SIGMAR1ANPEPFYN | |
| Dioxane SCHEMBL3943750 | 0.87 | PLAU (0.56) | PLAUIDO1SIGMAR1ANPEPFYN | |
| SCHEMBL20402534 | 0.86 | PLAU (0.54) | PLAUIDO1SIGMAR1FYNHTR2A | |
| Azobenzene SCHEMBL26642263 | 0.83 | ALDH1A1 (0.52) | PLAUIDO1SIGMAR1ANPEPFYN | |
| Azobenzene SCHEMBL26642269 | 0.83 | ALDH1A1 (0.52) | PLAUIDO1SIGMAR1ANPEPFYN | |
| SCHEMBL30368725 | 0.82 | PLAU (1.00) | PLAUANPEPCA1CA2DRD2 | |
| SCHEMBL42952 | 0.82 | PLAU (1.00) | PLAUANPEPCA1CA2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2439 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534498-B2 | Compounds for use as apelin receptor antagonists | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2026-01-27 | — | — | US | claimed |
| US-20240279280-A1 | COMPOUNDS FOR USE AS APELIN RECEPTOR ANTAGONISTS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-08-22 | — | — | US | claimed |
| US-11976137-B2 | Compounds for use as apelin receptor antagonists | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-05-07 | — | — | US | claimed |
| US-20240115553-A1 | COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY | AZEVAN PHARMACEUTICALS, INC. (US) | 2024-04-11 | — | — | US | claimed |
| CN-115377291-B | Bottom-up 2D/3D perovskite heterojunction, preparation method thereof and application thereof in perovskite solar cell | 重庆大学 | 2024-02-02 | — | — | CN | claimed |
| CN-112939895-B | Glycyl amine derivative and preparation method and application thereof | 桂林医学院 | 2022-11-04 | — | — | CN | claimed |
| CN-114539234-A | Synthesis method and application of C5-2-fatty amino pyrimidine azole compound | 深圳湾实验室 | 2022-05-27 | — | — | CN | claimed |
| US-11319306-B2 | Compositions and methods for treating neurodegenerative diseases | AZEVAN PHARMACEUTICALS, INC. (US) | 2022-05-03 | — | — | US | claimed |
| CN-113801033-B | Synthesis method of 2-aminoindan or derivatives thereof | 苏州欣诺科生物科技有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-113801033-A | Synthesis method of 2-aminoindan or derivatives thereof | 苏州欣诺科生物科技有限公司 | 2021-12-17 | — | — | CN | claimed |
| EP-0861837-A1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-02 | — | — | EP | claimed |
| WO-1997020806-A1 | INDANE COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTI-INFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IE) | 1997-06-12 | — | — | WO | claimed |
| WO-1997020802-A1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LIMITED (IE) | 1997-06-12 | — | — | WO | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
| EP-0317321-B1 | INDAN DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1993-01-20 | — | — | EP | claimed |
| CN-1017622-B | INDAN DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | TANABE SEIYAKU CO (JP) | 1992-07-29 | — | — | CN | claimed |
| CN-1033800-A | Indan derivative and its preparation method | TANABE SEIYAKU CO (JP) | 1989-07-12 | — | — | CN | claimed |
| EP-0317321-A2 | Indan derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1989-05-24 | — | — | EP | claimed |
| EP-0001002-B1 | INDANAMINES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-08-12 | — | — | EP | claimed |
| EP-0001002-A1 | Indanamines, processes for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-03-07 | — | — | EP | claimed |