Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ESRRG | P62508 | 2/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941118 | 1.00 | KCNH2 (0.46) | KCNH2CA2MAPK1NR1H4LMNA | |
| SCHEMBL2343543 | 0.85 | CA2 (0.49) | CA2MAPK1PPARDPPARAPPARG | |
| SCHEMBL11050992 | 0.84 | GRIK1 (0.56) | CA2MAPK1PPARG | |
| SCHEMBL29650381 | 0.84 | GRIK1 (0.56) | CA2MAPK1PPARG | |
| SCHEMBL586255 | 0.83 | GRIK1 (0.58) | CA2MAPK1PPARG | |
| SCHEMBL27483782 | 0.82 | KCNH2 (0.46) | KCNH2NR1H4LMNAESRRGSLC13A5 | |
| SCHEMBL6943972 | 0.81 | KCNH2 (0.45) | KCNH2NR1H4LMNAESRRGSLC13A5 | |
| SCHEMBL6943978 | 0.81 | KCNH2 (0.45) | KCNH2NR1H4LMNAESRRGSLC13A5 | |
| SCHEMBL13008878 | 0.80 | NR1H4 (0.50) | KCNH2NR1H4LMNAESRRGSLC13A5 | |
| SCHEMBL5801002 | 0.80 | PPARG (0.57) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |