Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29650381 | 1.00 | GRIK1 (0.56) | GRIK1CPB2CYP1A2CA2MAPK1 | |
| SCHEMBL586255 | 0.98 | GRIK1 (0.58) | GRIK1CPB2CYP1A2CA2MAPK1 | |
| SCHEMBL1026190 | 0.93 | GRIK1 (0.64) | GRIK1CPB2CYP1A2CA2MAPK1 | |
| SCHEMBL30839920 | 0.89 | GRIK1 (0.55) | GRIK1CPB2MAPTRXFP1PTGES | |
| SCHEMBL8845789 | 0.89 | PTGES (0.56) | GRIK1CPB2CA2MAPK1MAPT | |
| SCHEMBL11305180 | 0.89 | GRIK1 (0.55) | GRIK1CPB2MAPTRXFP1PTGES | |
| SCHEMBL355603 | 0.89 | GRIK1 (0.55) | GRIK1CPB2MAPTRXFP1PTGES | |
| SCHEMBL10869949 | 0.89 | GRIK1 (0.55) | GRIK1CPB2MAPTRXFP1PTGES | |
| SCHEMBL5385323 | 0.89 | GRIK1 (0.55) | GRIK1CPB2MAPTRXFP1PTGES | |
| SCHEMBL8845872 | 0.89 | PTGES (0.56) | GRIK1CPB2CA2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464290-A | REMOVAL OF CONIFERYL BENZOATE AND ACETATE | SHISEIDO COMPANY LTD. (JP) | 1984-08-07 | — | — | US | disclosed |