SCHEMBL6941294

SCHEMBL6941294

CC1(C)OC[C@@H](COC(=O)OCI)O1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.49
ALDH1A1 P00352 2/20 0.36
NPSR1 Q6W5P4 1/20 0.35
TMEM97 Q5BJF2 2/20 0.35
SIGMAR1 Q99720 2/20 0.35
HTR7 P34969 1/20 0.35
DGAT1 O75907 1/20 0.31
APP P05067 1/20 0.31
F10 P00742 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.30
NAMPT P43490 3/20 0.30
ADORA3 P0DMS8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18395904 0.92 CA2 (0.56) CA2ALDH1A1NPSR1TMEM97SIGMAR1
SCHEMBL6943821 0.92 CA2 (0.56) CA2ALDH1A1NPSR1TMEM97SIGMAR1
SCHEMBL13651150 0.86 CA2 (0.50) CA2ALDH1A1NPSR1TMEM97SIGMAR1
SCHEMBL4132454 0.86 CA2 (0.50) CA2ALDH1A1NPSR1TMEM97SIGMAR1
SCHEMBL7042446 0.85 CA2 (0.53) CA2ALDH1A1NPSR1TMEM97SIGMAR1
SCHEMBL30697976 0.84 CA2 (0.49) CA2ALDH1A1NPSR1TMEM97SIGMAR1
SCHEMBL10441415 0.84 CA2 (0.51) CA2ALDH1A1NPSR1TMEM97SIGMAR1
SCHEMBL13063460 0.84 CA2 (0.51) CA2ALDH1A1NPSR1TMEM97SIGMAR1
SCHEMBL12513225 0.82 CA2 (0.53) CA2ALDH1A1NPSR1TMEM97SIGMAR1
SCHEMBL30401615 0.82 CA2 (0.47) CA2ALDH1A1NPSR1TMEM97SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973768-B1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-07-09 EP disclosed
US-6583164-B1 Lyophilized imidazole-1-yl or 1,2,4-triazole-1-yl quaternized with a alklycarbonyloxy alkyl group eliminated in vivo; a saccharide; 4-acetoxymethyl-1-(3-(2-oxo-3-(4-(1H-tetrazol-yl) phenyl)-1-imidazolydinyl)butyl)-1H-1,2,4-triazolium chloride TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-24 US disclosed
US-6407129-B1 INJECTABLE QUATERNIZED SALT FUNGICIDES; WATER SOLUBILITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
EP-1120116-A1 ANTIMYCOTIC DRUG COMPOSITION Takeda Chemical Industries, Ltd. (JP) 2001-08-01 EP disclosed