Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MSR1 | P21757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934825 | 0.87 | ALOX15 (0.42) | ALOX15NFE2L2ALDH1A1KDM4ETSHR | |
| SCHEMBL8059226 | 0.74 | ALOX15 (0.67) | ALOX15NFE2L2ALDH1A1TSHRTDP1 | |
| SCHEMBL4941959 | 0.73 | ALOX15 (0.61) | ALOX15NFE2L2ALDH1A1TSHRTDP1 | |
| SCHEMBL7930882 | 0.71 | ALOX15 (0.49) | ALOX15NFE2L2ALDH1A1KDM4ETSHR | |
| SCHEMBL6485590 | 0.71 | ALOX15 (0.43) | ALOX15NFE2L2ALDH1A1KDM4ETSHR | |
| SCHEMBL4940586 | 0.69 | ALOX15 (0.52) | ALOX15NFE2L2ALDH1A1KDM4ETSHR | |
| SCHEMBL14450995 | 0.68 | TAAR1 (0.45) | ALOX15ALDH1A1KDM4ETSHR | |
| SCHEMBL17710688 | 0.68 | ALOX15 (0.44) | ALOX15NFE2L2ALDH1A1 | |
| SCHEMBL21596585 | 0.68 | ALOX15 (0.44) | ALOX15NFE2L2ALDH1A1KDM4ETSHR | |
| SCHEMBL17861077 | 0.68 | ALOX15 (0.51) | ALOX15NFE2L2ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |