Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MSR1 | P21757 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941308 | 0.87 | ALOX15 (0.41) | ALOX15ALDH1A1KDM4ETSHRNFE2L2 | |
| SCHEMBL6937909 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1GAAMAPTL3MBTL1 | |
| SCHEMBL4940586 | 0.77 | ALOX15 (0.52) | ALOX15ALDH1A1KDM4ETSHRNFE2L2 | |
| SCHEMBL14450995 | 0.76 | TAAR1 (0.45) | ALOX15ALDH1A1KDM4ETSHR | |
| SCHEMBL6942396 | 0.76 | TYR (0.42) | ALDH1A1TDP1GAAMAPTL3MBTL1 | |
| SCHEMBL6937591 | 0.75 | SLC6A2 (0.42) | ALDH1A1TDP1GAAMAPTL3MBTL1 | |
| SCHEMBL5604502 | 0.75 | FOLH1 (0.46) | ALOX15ALDH1A1KDM4ETSHRNFE2L2 | |
| SCHEMBL585340 | 0.75 | FOLH1 (0.46) | ALOX15ALDH1A1KDM4ETSHRNFE2L2 | |
| SCHEMBL5604934 | 0.75 | FOLH1 (0.46) | ALOX15ALDH1A1KDM4ETSHRNFE2L2 | |
| SCHEMBL9956686 | 0.75 | ALOX15 (0.43) | ALOX15ALDH1A1KDM4ETSHRNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |