Methacrylic Acid

Methacrylic Acid

SCHEMBL6941757

C=C(C)C(=O)O.CN(C)C.COS(=O)(=O)O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL3677811 0.93 ALDH1A1 (0.42) ALDH1A1TDP1
Methacrylic Acid SCHEMBL28470137 0.91 ALDH1A1 (0.40) ALDH1A1TDP1
Methacrylic Acid SCHEMBL11406486 0.85 TDP1 (0.36) ALDH1A1TDP1
Methacrylic Acid SCHEMBL11406490 0.85 TDP1 (0.36) ALDH1A1TDP1
Trimethylammonium SCHEMBL1232752 0.84 TDP1 (0.52) ALDH1A1TDP1
Trimethylammonium SCHEMBL1232753 0.84 TDP1 (0.52) ALDH1A1TDP1
Methacrylic Acid SCHEMBL28094163 0.84 ALDH1A1 (0.32) ALDH1A1
Trimethylammonium SCHEMBL140641 0.80 CA2 (0.41) TDP1
Methacrylic Acid SCHEMBL28229822 0.80 TDP1 (0.44) ALDH1A1TDP1
Trimethylammonium SCHEMBL10696615 0.80 CA2 (0.41) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1206181-B1 COMPOSITION CONTAINING AN ACTIVE SUBSTANCE, PRODUCTION AND USE THEREOF GOLDSCHMIDT AG TH (DE) 2003-11-12 EP disclosed
EP-1206181-A1 COMPOSITION CONTAINING AN ACTIVE SUBSTANCE, PRODUCTION AND USE THEREOF Goldschmidt AG (DE) 2002-05-22 EP disclosed
WO-2001010212-A1 COMPOSITION CONTAINING AN ACTIVE SUBSTANCE, PRODUCTION AND USE THEREOF GOLDSCHMIDT AG (DE) 2001-02-15 WO disclosed