Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.64 |
| ▸ | MMP9 | P14780 | 2/20 | 0.58 |
| ▸ | ITGAV | P06756 | 3/20 | 0.58 |
| ▸ | PLAU | P00749 | 2/20 | 0.55 |
| ▸ | HPN | P05981 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941856 | 1.00 | ITGB3 (0.64) | ITGB3ITGA2BMMP9ITGAVPLAU | |
| SCHEMBL7752629 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2BITGAV | |
| SCHEMBL7752361 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2BITGAV | |
| SCHEMBL27461966 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2BITGAV | |
| SCHEMBL7665921 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BMMP9PLAUHPN | |
| SCHEMBL8458591 | 0.83 | ITGB3 (0.75) | ITGB3ITGA2BITGAV | |
| SCHEMBL8458584 | 0.83 | ITGB3 (0.75) | ITGB3ITGA2BITGAV | |
| SCHEMBL7674423 | 0.82 | MMP9 (0.57) | ITGB3ITGA2BMMP9PLAUHPN | |
| SCHEMBL7398404 | 0.80 | ITGB3 (0.79) | ITGB3ITGA2BITGAV | |
| SCHEMBL7663345 | 0.79 | ITGB3 (0.69) | ITGB3ITGA2BMMP9ITGAVPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957908-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-0957908-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998025601-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-06-18 | — | — | WO | disclosed |