SCHEMBL6941870

SCHEMBL6941870

O=C(O)c1cccc(-c2ccccc2-c2ccccc2-c2ccccc2-c2cccc(C(=O)O)c2C(=O)O)c1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
ALOX15 P16050 1/20 0.59
MAPT P10636 2/20 0.59
LMNA P02545 1/20 0.59
HNF4A P41235 1/20 0.55
HSD17B10 Q99714 1/20 0.54
MYC P01106 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
FOLH1 Q04609 1/20 0.53
AKR1C3 P42330 1/20 0.52
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5321232 1.00 ALDH1A1 (0.59) ALDH1A1ALOX15MAPTLMNAHNF4A
SCHEMBL5321419 1.00 ALDH1A1 (0.59) ALDH1A1ALOX15MAPTLMNAHNF4A
SCHEMBL63603 0.95 HSD17B10 (0.58) ALDH1A1ALOX15MAPTLMNAHNF4A
SCHEMBL809021 0.93 FOLH1 (0.61) ALDH1A1ALOX15MAPTLMNAHNF4A
SCHEMBL5554145 0.93 HSD17B10 (0.56) ALDH1A1ALOX15MAPTLMNAHNF4A
Water SCHEMBL7131144 0.93 HSD17B10 (0.56) ALDH1A1ALOX15MAPTLMNAHNF4A
SCHEMBL31327322 0.92 HNF4A (0.63) ALDH1A1ALOX15MAPTLMNAHNF4A
SCHEMBL31212508 0.92 HNF4A (0.63) ALDH1A1ALOX15MAPTLMNAHNF4A
SCHEMBL31327312 0.92 HNF4A (0.63) ALDH1A1ALOX15MAPTLMNAHNF4A
SCHEMBL6425646 0.92 HNF4A (0.63) ALDH1A1ALOX15MAPTLMNAHNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1288191-A2 Novel aromatic diamine and polyimide thereof Mitsui Chemicals, Inc. (JP) 2003-03-05 EP disclosed
US-6159654-A Negative photosensitive polymer composition of a thermosetting polymer precursor curable by cyclodehydration upon heating KABUSHIKI KAISHA TOSHIBA (JP) 2000-12-12 US disclosed
US-6001517-A A THERMOSETTING POLYMER WHICH CAN BE CURED THROUGH CYCLODEHYDRATION UPON HEATING AND A CURE ACCELERATOR WHICH CAN BE DEACTIVATED OF ITS CURE ACCELERATION PROPERTY BY IRRIDIATION OF LIGHT KABUSHIKI KAISHA TOSHIBA (JP) 1999-12-14 US disclosed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 US disclosed