Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694672 | 0.85 | ALDH1A1 (0.43) | L3MBTL1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL698175 | 0.85 | L3MBTL1 (0.53) | L3MBTL1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL694009 | 0.83 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL693736 | 0.83 | L3MBTL1 (0.53) | L3MBTL1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL698304 | 0.82 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL3105659 | 0.79 | NPC1 (0.53) | L3MBTL1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL694717 | 0.79 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL693835 | 0.79 | ALDH1A1 (0.55) | L3MBTL1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL3110561 | 0.79 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL699564 | 0.78 | L3MBTL1 (0.57) | L3MBTL1SMN1; SMN2LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421838-A2 | ARYLSULFONAMIDE CCR3 ANTAGONISTS | Axikin Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123960-A2 | ARYLSULFONAMIDE CCR3 ANTAGONISTS | AXIKIN PHARMACEUTICALS, INC. (US) | 2010-10-28 | — | — | WO | disclosed |