Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946919 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BHRH4TSHRSIGMAR1 | |
| SCHEMBL6950238 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2BHRH4OPRM1 | |
| SCHEMBL7445038 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BHRH4TSHROPRM1 | |
| SCHEMBL6420263 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BOPRM1OPRK1 | |
| SCHEMBL6420268 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BOPRM1OPRK1 | |
| SCHEMBL6951463 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL538078 | 0.77 | ITGB3 (0.47) | ITGB3ITGA2BOPRM1HSD17B1 | |
| SCHEMBL538357 | 0.77 | ITGB3 (0.47) | ITGB3ITGA2BOPRM1HSD17B1 | |
| SCHEMBL6675207 | 0.76 | ITGB3 (0.67) | ITGB3ITGA2B | |
| SCHEMBL6674870 | 0.76 | ITGB3 (0.62) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |