Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913177 | 0.76 | AKR1C1 (0.34) | OPRK1 | |
| SCHEMBL596692 | 0.75 | CHRM2 (0.42) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL978448 | 0.73 | CHRM2 (0.41) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL21167253 | 0.73 | CHRM2 (0.41) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL21496090 | 0.72 | SLC6A2 (0.40) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL18428490 | 0.72 | CHRM2 (0.40) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL9717862 | 0.72 | OPRM1 (0.46) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL18428492 | 0.72 | CHRM2 (0.40) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL7105607 | 0.72 | CHRM2 (0.40) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL1153253 | 0.72 | CHRM2 (0.40) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043307-B1 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | GRUENENTHAL GMBH (DE) | 2003-06-04 | — | — | EP | disclosed |