SCHEMBL6942518

SCHEMBL6942518

C1=C(CCc2ccccc2)O1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.48
MAOB P27338 4/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 2/20 0.46
CYP2A6 P11509 1/20 0.46
HTR2A P28223 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
KCNH2 Q12809 2/20 0.44
FFAR1 O14842 1/20 0.43
CALM1 P0DP23 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9741303 0.80 ALDH1A1 (0.69) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL62125 0.80 ALDH1A1 (0.69) MAOAMAOBALDH1A1HPGDALOX15
Benzene SCHEMBL3440179 0.80 ALDH1A1 (0.69) MAOAMAOBALDH1A1HPGDALOX15
Hydrogen Sulfide SCHEMBL5468201 0.76 ALDH1A1 (0.65) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL742615 0.76 ALDH1A1 (0.65) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL25403475 0.76 ALDH1A1 (0.65) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL1793454 0.76 ALDH1A1 (0.65) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL11747668 0.76 ALDH1A1 (0.65) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL3759913 0.76 ALDH1A1 (0.65) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL25402413 0.76 ALDH1A1 (0.65) MAOAMAOBALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54100367-A None JP disclosed
EP-1074544-B1 Process for production of 3-(3-pyridyl)-1-propanol derivatives KANEKA CORP (JP) 2003-08-27 EP disclosed
US-6388086-B1 REACTING W 3-METHYLPYRIDINE WITH BASE; THEN EPOXY COMPOUND KANEKA CORPORATION (JP) 2002-05-14 US disclosed
EP-1074544-A1 Process for production of 3-(3-pyridyl)-1-propanol derivatives KANEKA CORPORATION (JP) 2001-02-07 EP disclosed
US-4236012-A ANALGESICS, ANTIINFLAMMATORY AGENTS, MUSCLE RELAXANTS Nippon Chemiphar Company, Limited (JP) 1980-11-25 US disclosed
JP-S54100367-A 5-PHENETHYL-2-OXAZOLIDONE DERIVATIVE AND ITS PREPARATION NIPPON CHEMIPHAR CO LTD 1979-08-08 JP disclosed