Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADA | P00813 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942605 | 1.00 | HTR7 (0.45) | HTR7ARADRB2ADRB1ADRB3 | |
| SCHEMBL4511606 | 0.84 | HTR7 (0.51) | HTR7ARCDC7MTNR1AMTNR1B | |
| SCHEMBL6940163 | 0.82 | ADRB2 (0.41) | ADRB2ADRB1ADRB3MAPT | |
| SCHEMBL6940159 | 0.82 | ADRB2 (0.41) | ADRB2ADRB1ADRB3MAPT | |
| SCHEMBL6933495 | 0.80 | ADA (0.56) | HTR7ADA | |
| SCHEMBL6933500 | 0.80 | CDK4 (0.45) | MAPT | |
| SCHEMBL6933502 | 0.80 | CDK4 (0.45) | MAPT | |
| SCHEMBL6938432 | 0.76 | HTR7 (0.49) | HTR7MAPTADA | |
| SCHEMBL6938431 | 0.76 | HTR7 (0.49) | HTR7MAPTADA | |
| Ammonia Solution, Strong SCHEMBL27732810 | 0.74 | HTR7 (0.57) | HTR7ARCDC7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |
| EP-1161429-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055155-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-21 | — | — | WO | disclosed |