Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 6/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 4/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942839 | 1.00 | CYP1B1 (0.66) | CYP1B1MAOBBCHETDP1MAPT | |
| SCHEMBL10861302 | 0.83 | TDP1 (0.62) | CYP1B1MAOBBCHETDP1MAPT | |
| SCHEMBL13911500 | 0.81 | CYP1B1 (0.61) | CYP1B1MAOBBCHETDP1MAPT | |
| SCHEMBL30028217 | 0.81 | MAOB (0.62) | CYP1B1MAOBBCHETDP1MAPT | |
| SCHEMBL2561307 | 0.81 | MAOB (0.62) | CYP1B1MAOBBCHETDP1MAPT | |
| SCHEMBL2561308 | 0.81 | MAOB (0.62) | CYP1B1MAOBBCHETDP1MAPT | |
| SCHEMBL6733848 | 0.80 | MAOB (0.85) | CYP1B1MAOBBCHEMAPTALDH1A1 | |
| SCHEMBL6733854 | 0.80 | MAOB (0.85) | CYP1B1MAOBBCHEMAPTALDH1A1 | |
| SCHEMBL3082127 | 0.80 | CYP1B1 (1.00) | CYP1B1MAOBBCHETDP1MAPT | |
| SCHEMBL726453 | 0.80 | ALDH1A1 (0.67) | MAOBBCHETDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902011-B1 | GAMMA-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-5981794-A | REACTING A BETA-BENZOYLACRYLIC ACID DERIVATIVE WITH A 1-ARYLETHYLAMINE DERIVATIVE | KANEKA CORPORATION (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0902011-A1 | $g(g)-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME | Kaneka Corporation (JP) | 1999-03-17 | — | — | EP | disclosed |