Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942872 | 1.00 | KMT2A (0.40) | KMT2APTGS1PTGS2CA1CA2 | |
| SCHEMBL6941832 | 0.84 | CA2 (0.50) | KMT2APTGS1PTGS2CA1CA2 | |
| SCHEMBL6941837 | 0.84 | CA2 (0.50) | KMT2APTGS1PTGS2CA1CA2 | |
| SCHEMBL7653952 | 0.76 | CDK1 (0.57) | KMT2APTGS1PTGS2GAAMAPT | |
| SCHEMBL17825638 | 0.76 | KMT2A (0.58) | KMT2APTGS1PTGS2CA1CA2 | |
| SCHEMBL17825688 | 0.76 | KMT2A (0.58) | KMT2APTGS1PTGS2CA1CA2 | |
| SCHEMBL6151581 | 0.75 | KDM4E (0.52) | KMT2ACA1CA2CA9CA5A | |
| SCHEMBL7924986 | 0.75 | LMNA (0.45) | KMT2ACA1CA2CA9CA5A | |
| SCHEMBL21962901 | 0.74 | KMT2A (0.39) | KMT2ACA1CA2CA9CA5A | |
| SCHEMBL7875914 | 0.74 | GAA (0.54) | KMT2ACA1CA2CA9CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912093-B1 | (HETERO)ARYL SULPHONYL UREAS WITH AN IMINOFUNCTION, THE PREPARATION AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6410482-B1 | CONTROLLING WEEDS, GRASSES; COMPOUND CONTAINING PYRIMIDINE RING | HOECHST SCHERING AGREVO GMBH (DE) | 2002-06-25 | — | — | US | disclosed |