⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927256 | 0.79 | — | — | |
| SCHEMBL127281 | 0.75 | — | — | |
| SCHEMBL694289 | 0.70 | — | — | |
| SCHEMBL702714 | 0.68 | — | — | |
| SCHEMBL5095094 | 0.68 | — | — | |
| SCHEMBL690348 | 0.68 | — | — | |
| SCHEMBL3395205 | 0.68 | — | — | |
| SCHEMBL183542 | 0.68 | — | — | |
| SCHEMBL75115 | 0.68 | — | — | |
| SCHEMBL4032027 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101914080-B | Benzofuran-3-ketone substitute phenyl compound as well as preparation method and application | UNIV SHANGHAI JIAOTONG | 2012-10-03 | — | — | CN | claimed |
| CN-101914080-A | Benzofuran-3-ketone substitute phenyl compound as well as preparation method and application | UNIV SHANGHAI JIAOTONG | 2010-12-15 | — | — | CN | claimed |
| EP-2948188-B1 | NEURONAL IMAGING AND TREATMENT | TYLERTON INT HOLDINGS INC (VG) | 2021-09-08 | — | — | EP | disclosed |
| CN-110272400-A | The synthetic method of 2- trifluoromethyl substituted furan compound and its derivative | 福州大学 | 2019-09-24 | — | — | CN | disclosed |
| CN-104994885-B | Method and composition for radiohalogen protein labeling | 基因泰克公司 | 2017-09-29 | — | — | CN | disclosed |
| US-9486546-B2 | Methods and compositions for radiohalogen protein labeling | GENENTECH, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9393327-B2 | Methods and compositions for radiohalogen protein labeling | GENENTECH, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20160002121-A1 | METHODS AND COMPOSITIONS FOR RADIOHALOGEN PROTEIN LABELING | GENENTECH, INC. (US) | 2016-01-07 | — | — | US | disclosed |
| US-20150366523-A1 | NEURONAL IMAGING AND TREATMENT | TYLERTON INTERNATIONAL HOLDINGS INC. (VG) | 2015-12-24 | — | — | US | disclosed |
| EP-2948188-A1 | NEURONAL IMAGING AND TREATMENT | Tylerton International Holdings Inc. (VG) | 2015-12-02 | — | — | EP | disclosed |
| EP-2934602-A1 | METHODS AND COMPOSITIONS FOR RADIOHALOGEN PROTEIN LABELING | Genentech, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| EP-0885017-A2 | USE OF LABELLED CCK-B RECEPTOR LIGANDS FOR THE DETECTION AND LOCALIZATION OF MALIGNANT HUMAN TUMOURS | MALLINCKRODT MEDICAL, INC. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1998033531-A1 | METHOD FOR THE DETECTION AND LOCALIZATION OF MALIGNANT HUMAN TUMOURS | MALLINCKRODT MEDICAL, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| WO-1997031657-A2 | USE OF LABELLED CCK-B RECEPTOR LIGANDS FOR THE DETECTION AND LOCALIZATION OF MALIGNANT HUMAN TUMORS | MALLINCKRODT MEDICAL, INC. (US) | 1997-09-04 | — | — | WO | disclosed |
| WO-1996023527-A9 | METHOD FOR THE DETECTION AND LOCALIZATION OF MALIGNANT HUMAN TUMOURS | — | 1996-10-03 | — | — | WO | disclosed |
| WO-1996023527-A1 | METHOD FOR THE DETECTION AND LOCALIZATION OF MALIGNANT HUMAN TUMOURS | MALLINCKRODT MEDICAL, INC. (US) | 1996-08-08 | — | — | WO | disclosed |
| EP-0595743-A1 | Bihaptinic derivatives for binding for technetium or rhenium, process for their preparation, application for diagnosis and therapy, kits and immunological reactants comprising them | IMMUNOTECH PARTNERS:Société Anonyme dite (FR) | 1994-05-04 | — | — | EP | disclosed |
| US-5242680-A | Diagnostic and therapeutic | MERCK & CO., INC. (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0524722-A1 | Thiol-reactive maleimido-based radiolabeling reagents | MERCK & CO. INC. (US) | 1993-01-27 | — | — | EP | disclosed |
| US-4197309-A | AND THEIR OXIMES, USED TO INDUCE URICOSIC EFFECT WITHOUT DIURESIS | ALBERT ROLAND S.A. (FR) | 1980-04-08 | — | — | US | disclosed |