SCHEMBL69429

SCHEMBL69429

Oc1c(Cl)cc(C2(c3cc(Cl)c(O)c(Cl)c3)CCCCC2)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.59
ESR1 P03372 4/20 0.48
ESR2 Q92731 4/20 0.48
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 3/20 0.42
TSHR P16473 2/20 0.42
TTR P02766 2/20 0.42
CYP3A4 P08684 1/20 0.42
RECQL P46063 1/20 0.42
THRB P10828 1/20 0.39
ALOX15 P16050 2/20 0.39
ALOX12 P18054 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
MPI P34949 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4245311 0.98 ACHE (0.55) ACHEESR1ESR2ALDH1A1HSD17B10
SCHEMBL10788082 0.88 ESR1 (0.56) ACHEESR1ESR2ALDH1A1HSD17B10
SCHEMBL30442737 0.87 ACHE (0.76) ACHEESR1ESR2ALDH1A1HSD17B10
SCHEMBL10799203 0.87 ACHE (0.76) ACHEESR1ESR2ALDH1A1HSD17B10
SCHEMBL297822 0.87 ACHE (0.76) ACHEESR1ESR2ALDH1A1HSD17B10
SCHEMBL10787766 0.87 ACHE (0.76) ACHEESR1ESR2ALDH1A1HSD17B10
SCHEMBL297845 0.82 ACHE (0.50) ACHEESR1ESR2SLC6A4SLC6A3
SCHEMBL31287197 0.82 ACHE (0.50) ACHEESR1ESR2SLC6A4SLC6A3
SCHEMBL30443121 0.82 ACHE (0.50) ACHEESR1ESR2ALDH1A1HSD17B10
SCHEMBL297680 0.82 ACHE (0.50) ACHEESR1ESR2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 675 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3235850-B1 POLYCARBONATE COPOLYMER AND PREPARATION METHOD THEREFOR SAMYANG CORP (KR) 2020-02-12 EP claimed
US-10081708-B2 Polycarbonate copolymer and preparation method therefor SAMYANG CORPORATION (KR) 2018-09-25 US claimed
US-20180162994-A1 Polycarbonate Copolymer And Preparation Method Therefor SAMYANG CORPORATION (KR) 2018-06-14 US claimed
EP-3235850-A1 POLYCARBONATE COPOLYMER AND PREPARATION METHOD THEREFOR Samyang Corporation (KR) 2017-10-25 EP claimed
US-20090163692-A1 AROMATIC POLYETHERS GENERAL ELECTRIC COMPANY (US) 2009-06-25 US claimed
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1560871-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP claimed
WO-2004041907-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-05-21 WO claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
US-5283314-A Polymerizing an oligomer of a dihydric phenol and a branching agent with a dihydric alcohol and a monohydric phenol with stirring IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-02-01 US claimed
US-5041523-A Interfacial polycondensation using divalent phenol and branching agent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-08-20 US claimed
EP-4692236-A1 THERMOPLASTIC RESIN COMPOSITION HAVING EXCELLENT HARDNESS, DISCOLORATION RESISTANCE, AND IMPACT RESISTANCE, AND MOLDED ARTICLE COMPRISING SAME Samyang Corporation (KR) 2026-02-11 EP disclosed
EP-0113870-A1 Copolyester-carbonate blends exhibiting improved processability GENERAL ELECTRIC COMPANY (US) 1984-07-25 EP disclosed
US-4140730-A FLAME RESISTANT, ELECTRICAL INSULATOR, MIXTURE OF HALOGENATED POLYCARBONATE AND BISPHENOL A POLYCARBONATE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-20 US disclosed