Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 9/20 | 0.47 |
| ▸ | APOB | P04114 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 5/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582780 | 0.93 | MTTP (0.46) | MTTPAPOBKDM4EALDH1A1LMNA | |
| SCHEMBL2589160 | 0.87 | MTTP (0.43) | MTTPAPOBKDM4EALDH1A1LMNA | |
| SCHEMBL6698014 | 0.85 | CA1 (0.52) | MTTPAPOBKDM4EALDH1A1LMNA | |
| SCHEMBL2763032 | 0.83 | SLC6A9 (0.41) | MTTPAPOBKDM4EALDH1A1LMNA | |
| SCHEMBL6585667 | 0.83 | MTTP (0.47) | MTTPAPOBKDM4EALDH1A1LMNA | |
| SCHEMBL14511118 | 0.79 | MTTP (0.52) | MTTPAPOBKDM4EALDH1A1LMNA | |
| SCHEMBL2588205 | 0.78 | HIF1A (0.64) | MTTPAPOBKDM4EALDH1A1LMNA | |
| SCHEMBL14511122 | 0.78 | NOTUM (0.54) | MTTPAPOBKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6582091 | 0.77 | MTTP (0.49) | MTTPAPOBKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6581808 | 0.77 | MTTP (0.49) | MTTPAPOBKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317431-A2 | POLYARYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020501-A2 | POLYARYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-03-14 | — | — | WO | disclosed |