Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | APOB | P04114 | 2/20 | 0.39 |
| ▸ | MTTP | P55157 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582780 | 0.91 | MTTP (0.46) | SLC6A9APOBMTTPMAPTKDM4E | |
| SCHEMBL6942922 | 0.83 | MTTP (0.47) | SLC6A9APOBMTTPMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5740569 | 0.73 | MTTP (0.48) | SLC6A9MCHR1APOBMTTPMAPT | |
| SCHEMBL2589160 | 0.71 | MTTP (0.43) | APOBMTTPMAPTKDM4EALDH1A1 | |
| SCHEMBL7086631 | 0.71 | NPC1 (0.54) | APOBMTTPLMNA | |
| SCHEMBL6698014 | 0.71 | CA1 (0.52) | APOBMTTPMAPTKDM4EALDH1A1 | |
| SCHEMBL7133291 | 0.70 | NPC1 (0.56) | APOBKDM4ELMNA | |
| SCHEMBL6792746 | 0.70 | PTGS1 (0.57) | APOBMTTPLMNA | |
| SCHEMBL6580655 | 0.70 | HIF1A (0.56) | — | |
| SCHEMBL7079790 | 0.70 | S1PR1 (0.51) | S1PR1APOBMTTPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317431-B1 | POLYARYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-20 | — | — | EP | disclosed |